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SUTENT is used to treat GIST (gastrointestinal stromal tumor). This is a rare cancer of the stomach, bowel, or esophagus. SUTENT is used when the medicine Gleevec^® (imatinib mesylate) did not stop the cancer from growing or when you cannot take Gleevec. Gleevec is a registered trademark of Novartis AG.

First Resource offers many services to help you access Pfizer medicines. Enrollment is easy. A simple phone call can start the process. If you need to take a Pfizer cancer medicine, First Resource offers these services:

Reimbursement assistance—A First Resource counselor can help you understand your coverage and reimbursement options. One of the ways the counselor can help includes benefit verification, in which your counselor will review your insurance benefits to see how you are covered for the medicine you need
Alternate funding assistance—First Resource can help you find other sources of funding (if available) if you need them. You may also be able to receive a temporary supply of medication from Pfizer while you apply for alternate funding
Appeals assistance—First Resource helps with the appeals process if your insurance company underpays a claim or denies coverage. First Resource counselors help monitor and track the status of each appeal until a decision is made

Medicines available through First Resource include SUTENT. For a complete list, please see www.PfizerHelpfulAnswers.com.

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Pfizer and its agents cannot guarantee the accuracy of information provided by insurers, nor do they guarantee insurance reimbursement. Because many factors influence reimbursement, program staff cannot anticipate or resolve all issues raised by program callers. Pfizer reserves the right to modify or discontinue the program, without notice, at any time.

SUTENT is used to treat advanced kidney cancer (advanced renal cell carcinoma or RCC).

SUTENT is used to treat GIST (gastrointestinal stromal tumor). This is a rare cancer of the stomach, bowel, or esophagus. SUTENT is used when the medicine Gleevec^® (imatinib mesylate) did not stop the cancer from growing or when you cannot take Gleevec.

Important Safety Information

SUTENT can cause serious liver problems, including death.

Tell your healthcare provider right away if you develop any of the following during treatment with SUTENT: itching; yellow eyes or skin; dark urine; or pain or discomfort in the right upper stomach area.

Your healthcare provider should do blood tests to check your liver function before you start taking SUTENT and during treatment.

SUTENT may cause heart problems. Heart problems may include heart failure, heart muscle problems (cardiomyopathy) or abnormal heart rhythm changes. Tell your healthcare provider if you feel dizzy, faint, very tired, have abnormal heartbeats, are short of breath, or have swollen feet and ankles while taking SUTENT.

SUTENT may cause high blood pressure. Your healthcare provider may check your blood pressure, and may treat you for high blood pressure.

SUTENT may cause bleeding sometimes leading to death. Tell your healthcare provider right away if you have any of following during treatment with SUTENT: serious bleeding; painful swollen stomach (abdomen); vomiting blood; black sticky stools; bloody urine; headache or change in your mental status.

SUTENT may cause hormone problems, including thyroid and adrenal gland problems. Your healthcare provider may do tests to check your thyroid and adrenal gland function during SUTENT treatment.

SUTENT may harm an unborn baby (cause birth defects). Do not become pregnant. If you do, tell your healthcare provider right away. Stop taking SUTENT. Do not breastfeed while taking SUTENT.

Using SUTENT with other medicines can cause serious side effects. Tell your healthcare provider about all the medicines, vitamins, or herbal products you use.

You may have side effects or reactions to SUTENT. For most patients, these are moderate and may be managed, though some can be serious. Your healthcare provider may change your dose or stop your treatment. Some of the most common side effects include tiredness, weakness, fever, diarrhea, nausea, vomiting, mouth sores, upset stomach, abdominal pain, constipation, skin or hair changes, taste changes, swelling, loss of appetite, and bleeding, such as from the nose or cuts. Tell your healthcare provider if you have any swelling or bleeding. Be sure to tell your healthcare provider about any new side effects you have, as well as any change or increase in any side effect.

Gleevec is a registered trademark of Novartis AG.

Please see patient Medication Guide and full prescribing information.

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The health information contained herein is provided for educational purposes only and is not intended to replace discussions with a health care provider. All decisions regarding patient care must be made with a health care provider, considering the unique characteristics of the patient.

This product information provided in this site is intended only for residents of the United States. The products discussed herein may have different labeling in different countries.